Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells, The Journal of Cell Biology | DeepDyve
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Abnormal nuclear shape and impaired mechanotransduction in emerin-deficient cells, The Journal of Cell Biology | DeepDyve
Emery-Dreifuss muscular dystrophy can be caused by mutations in the nuclear envelope proteins lamin A/C and emerin. We recently demonstrated that A-type lamin-deficient cells have impaired nuclear mechanics and altered mechanotransduction, suggesting two potential disease mechanisms (Lammerding, J., P.C. Schulze, T. Takahashi, S. Kozlov, T ...
Aug 29, 2005
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