"Humanity is greatly diminished whenever the unborn, or the undocumented, the unemployed, the unhealthy are excluded," Cardinal Blase Cupich said.

Pope Leo, a native of Chicago's south side and a long-time fan of his beloved but beleaguered White Sox, sent a video message on Saturday to a sellout crowd attending Catholic Mass in his honor at their hometown ballpark.

Cyd Smillie had the design and started adding Pope Leo XIV to the mural before he donned a White Sox cap at the Vatican earlier this week.