Israeli Iron Dome air defense system fire to intercept missiles over Tel Aviv as others explode and traces fly over Jerusalem during a missile attack by Iran in retaliation for deadly Israeli attacks on nuclear sites and military leaders.

Iran fired a new wave of missile attacks on Israel early Monday, triggering air raid sirens across the country as emergency services reported at least five killed and dozens more wounded in the fourth day of open warfare between the regional foes that showed no sign of slowing.