How cell skeleton defects can teach immunology

For immune cells, the actin cytoskeleton is more than a structural scaffold. Immune cells can migrate to sites of infection ...

Imunon’s IL-12 gene therapy changes “cold” tumour microenvironment to “hot”

Translational results bolster confidence as Phase III trial for IMNN-001 in advance epithelial ovarian cancer gets underway.
Technology Networks

Engineered Gut Bacteria Enhances Immune Response in Colorectal Cancer Models

Researchers have engineered a strain of gut-targeting bacteria that triggers immune responses in colorectal cancer models, ...

Penn’s CAR-T pioneer Carl June talks about the future of his award-winning work to train the body to fight cancer

Philadelphia’s pioneering cancer scientist, Carl June, has been honored with two awards in the last month for his seminal work engineering the body’s immune system to fight cancer. June has spent ...
RMD Open

Serum calprotectin and complement factor C3 are superior biomarkers of inflammation in early psoriatic arthritis as compared with C-reactive protein

Objectives C reactive protein (CRP) is frequently normal in psoriatic arthritis (PsA) despite active disease, complicating ...
Technology Networks

Innovative Drug Delivery Systems for Precision Medicine

This article explores innovative drug delivery strategies, including DNA barcoding, shape-engineered nanoparticles and ...