FierceBiotech21h
In 2 papers, researchers describe potential new neurodegenerative disease treatment approach
The team engineered genes to code for the RING constructs and delivered them to mice using an adenovirus vector, commonly ...
Hantavirus Alert: Two Mice from Trails at San Onofre State Beach Test Positive
San Diego County public health employees collected two mice from trails around San Onofre State Beach that tested positive ...
Hantavirus detected in mice at San Onofre State Beach
The potentially deadly hantavirus has been detected in two mice at San Onofre State Beach, San Diego County officials said ...
Cambridge Independent on MSN1d
Promising ‘Trojan horse’ potential therapies against Alzheimer’s and other diseases developed by Cambridge scientists
The TRIM21 therapies have been shown to remove toxic tau proteins and reduce symptoms of neurodegeneration in mice.
New therapy that targets and destroys tau tangles: A promising Alzheimer's disease treatment
Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.
The EMBO Journal4d
IF1 is a cold-regulated switch of ATP synthase hydrolytic activity to support thermogenesis in brown fat
How the hydrolytic activity of mitochondrial ATP synthase is modulated during brown adipose tissue (BAT) thermogenesis ...
eLife4d
Pathogenic LRRK2 causes age-dependent and region-specific deficits in ciliation, innervation and viability of cholinergic neurons
Pathogenic activating point mutations in the LRRK2 kinase cause autosomal-dominant familial Parkinsońs disease (PD). In cultured cells, mutant LRRK2 causes a deficit in de novo cilia formation and ...