News

CRISPRgenee: New method leads to a better understanding of cell functions

The 2020 Nobel Prize in Chemistry was awarded for the development of CRISPR/Cas9, a method also known as "gene scissors," ...
News-Medical.Net on MSN

Loss of key Y chromosome gene causes infertility in male mice

In a new study conducted at the University of Hawaiʻi at Mānoa, researchers from the John A. Burns School of Medicine (JABSOM) have shown that the loss of a key male fertility gene leads to ...

DNA folding more important for cell function than previously thought

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in ...
News-Medical.Net on MSN

Boosting PI31 to restore synaptic function and prevent neurodegeneration

One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the ...
AZoLifeSciences on MSN

Loss of Zfy Genes Explains Why Some Sperm Fail

A study at the University of Hawaiʻi at Mānoa by researchers from the John A. Burns School of Medicine (JABSOM) found that ...
Lupus Science & Medicine

Frequency-dependent and temporal variability of low-frequency fluctuations in patients with primary Sjögren’s syndrome

Objectives The central nervous system is a significant extraglandular target in primary Sjögren’s syndrome (pSS), often ...
eLife

Fast evolutionary turnover and overlapping variances of sex-biased gene expression patterns defy a simple binary sex classification of somatic tissues

Sex-biased gene expression in the body organs evolves rapidly, supporting a mosaic model of maleness and femaleness across tissues and thus challenging binary views of sex characteristics in mammals.