A mutation causes a defect in the production of exosomes, which has been shown to drive the progression of Alzheimer's ...

CAMBRIDGE, Mass. and SAN FRANCISCO, Sept. 17, 2025 /PRNewswire/ -- The laboratories of Dr. Kevin Bender and Dr. Nadav Ahituv ...

The flexible stalk region of sTREM2 binds the Ig-like domain, altering stability and ligand accessibility—a biochemically testable mechanism with broad implications for (s)TREM2 biology and rational ...

Proteins can be driven by mutations to self-assemble into agglomerates (composed of folded proteins) or aggregates ...

Scientists from the Gray Faculty of Medical & Health Sciences at Tel Aviv University introduced an innovative gene therapy method to treat impairments in hearing and balance caused by inner ear ...

In recent years, the U.S. Food and Drug Administration (FDA) has approved a wave of new therapies, including gene therapies, ...

Following a diagnosis, a Pennsylvania woman underwent genetic testing that revealed she had a very rare, inherited form of ALS — a diagnosis only about 500 people in the U.S. share.

A genetic deletion responsible for the rare “salmiak” pattern in cats has been identified, revealing new information about ...

Phase 1 data in healthy volunteers exceed expectations and support best-in-class potential, enabling Phase 2 advancement for ...

One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the ...