Boosting Klotho protein levels in mice improves physical and cognitive aging, offering potential for future longevity ...

Volume 17, Issue 6, on June 5, 2025, titled “Senescence caused by telomerase inactivation in myeloid, mesenchymal, and endothelial cells has distinct effects on cancer progression.” ...

A research team led by Professor Takuya Yamamoto (Department of Life Science Frontiers) and Professor Yasuhiro Yamada at the University of Tokyo has developed a novel in vivo system that reveals how ...

In a study published in Aging Cell, they tested senolytics in aging mice. Senolytics are drugs that can induce senescent cells to die through apoptosis, the typical process by which cells are removed.

A combination of high-resolution imaging and machine learning, also known as artificial intelligence (AI), can track cells ...

Microbiomes in older mice pumped out damaging metabolites that drove endothelial cell senescence, offering potential targets ...

They have enjoyed some success: mice with two mothers and no fathers were reported in 2004. But creating animals with two fathers and no mother has proved much harder.

By flipping an evolutionarily disabled genetic switch involved in vitamin A metabolism, researchers headed by a team at the National Institute of Biological Sciences, Beijing, have enabled ear ...