An 86-year-old man presented to the neurology clinic with 2 years of progressive memory loss and difficulty walking. An MRI showed microbleeds that appeared as hypointense foci throughout the ...

The administration recently announced a new payment model to align some Medicare Part B drug payments with international pricing benchmarks. Various factors could affect the model’s scope and impact.

A new pilot Medicaid program — GENEROUS — combines centralized pharmaceutical-coverage negotiations with most-favored-nation pricing in an effort to lower drug costs, but it has some limitations.

Explore this issue of The New England Journal of Medicine (Vol. 394 No. 6).

Explore this issue of The New England Journal of Medicine (Vol. 390 No. 4).

Guidelines recommend a trial of antiarrhythmic drugs before catheter ablation for persistent atrial fibrillation. Whether pulsed field ablation (PFA) may be a preferred initial treatment is ...

Blood-pressure reduction is the only proven treatment to prevent stroke. Whether a single pill that combines three ...

In this trial of arthroscopic partial meniscectomy for degenerative medial meniscal tear in adults, participant-reported and radiologic outcomes over 10 years of follow-up suggested no benefit and ...

A 76-year-old woman, who had a history of treated hepatitis C virus infection, presented with rapidly progressive kidney failure and a stroke. Palpable purpura on the legs was noted. A diagnosis ...

The author describes the scientific foundations and implications of the results of a randomized, controlled trial of Mim8, a new mimetic of factor VIIIa, to treat hemophilia A.

Whether treatment with balanced crystalloid fluid leads to better outcomes than 0.9% saline in children treated for septic ...

Explore this issue of The New England Journal of Medicine (Vol. 394 No. 3).