Michigan State will go on the road for its Big Ten opener against USC in Los Angeles on Saturday night. Can the Spartans pull off the upset?

Bill Belichick and the UNC football program endured a brutal 34-9 road loss to UCF on Saturday afternoon, dropping the Tar Heels to 2-2 on the year in the eight-time Super Bowl winner's first year as head coach.

Just under an hour before the scheduled 6:30 p.m. kickoff, fans were asked to leave the stadium and players left the field during warmups due to lightning detected in the area. Per NCAA rules, warmups and the game cannot resume until 30 minutes after the last lightning strike within eight miles of FirstBank Stadium.

An early showdown unfolds from aspiring Big Ten contenders and top-20 teams, as the 19th-ranked Indiana Hoosiers visit No. 9 Illinois for a night kick in Champaign.

A couple of Texas teams tango on Saturday, Sept. 20 at DKR-Texas Memorial Stadium in Austin, Texas where the No. 8 Longhorns host the Sam Houston Bearkats.

Both teams enter tonight's matchup with perfect 3-0 records as they face off in Bloomington at 7:30 p.m. ET on NBC.

Kickoff from Hard Rock Stadium in Florida is set for 7:30 p.m. ET. The Hurricanes are 7.5-point favorites, according to the latest Florida vs. Miami odds, while the over/under for total points scored is 51.5. Before making any Miami vs. Florida picks, make sure you check out the college football picks from the SportsLine Projection Model.

As the college football action on Saturday, Sept. 20 starts to wind down, there is a matchup at Folsom Field in Boulder, Colo. where the Wyoming Cowboys are visiting the Colorado Buffaloes.