Israeli Prime Minister Benjamin Netanyahu is on the mission of his lifetime. For years, the veteran leader has made the destruction of Iran’s nuclear program his top priority.

Tension in the Middle East remains high, as Iran and Israel exchange fire. Iran says that the U.S. is complicit in the initial Israeli strike on their nuclear program, Iran will no longer participate in the sixth round of nuclear talks with the U.

Iran and Israel targeted each other with airstrikes early on Saturday after Israel launched its biggest-ever offensive against its longtime foe in a bid to prevent it from developing a nuclear weapon.