Covalent BTK inhibitors and Bcl-2 inhibitors are primary treatments for CLL, but alternatives are needed for relapsed or refractory cases. Treatment sequencing is vital, with potential switches ...

Researchers have shed new light on how the structure of regulatory sequences in DNA is packaged in a cell. This work has implications for better understanding the role that gene sequences called ...

Regulatory DNA sequences contain information on the timing and level at which different genes are expressed. An ongoing challenge is to uncover the means by which this information is encoded and ...

High-throughput genome sequencing is changing the way we practice medicine by providing new abilities to identify the genetic causes of disease. DNA sequencing applications frequently rely on curated ...