Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or ...

A team led by researchers at the University of Cologne has identified a protein called ANKIB1 that acts as a volume dial for the body’s frontline immune defenses, controlling how strongly cells ...

Ubiquitin is a protein that is present throughout cellular tissues in eukaryotic organisms which plays a regulatory role in the processes of other proteins and is a versatile molecular signal. First ...

Scientists believe that in late-onset Alzheimer’s disease, Aβ clearance slows, causing the protein to accumulate in plaques. In the September 22 Nature Communications, researchers led by Michael ...

In October 2004, the Royal Swedish Academy of Sciences awarded the Nobel Prize in Chemistry to Aaron Ciechanover, Avram Hersko, and Irwin Rose "for the discovery of ubiquitin-mediated protein ...