Clinical portfolio, informed by deep and novel synapse biology and pharmacology insights, aims to strengthen neural connections through event-driven pharmacology Lead candidate zelquistinel is ...

Because synapses are responsible for passing information between neurons, these connections are vital for communication within and outside the brain. Therefore, understanding how they form, function, ...

Scientists have uncovered how a protein helps build and maintain vital brain connections, providing insights into the neurological problems experienced by people with a rare form of muscular dystrophy ...

Scientists at HHMI's Janelia Research Campus have discovered a new kind of synapse in the tiny hairs on the surface of neurons. The commonly overlooked protrusions called primary cilia contain special ...

The ability to regrow lost synapses can be life changing; for Derek Small, cofounder and CEO of the start-up Syndeio Biosciences, it holds personal relevance. Around a decade ago, Small watched his ...

Scientists at Yale and the University of Connecticut have taken a major step in understanding how animal brains make decisions, revealing a crucial role for electrical synapses in “filtering” sensory ...

Researchers have been trying to build artificial synapses for years in the hope of getting close to the unrivaled computational performance of the human brain. A new approach has now managed to design ...

Vesicle recycling in the presynaptic terminal at one end of a neuron, showing the role of dynamin during the last step of endocytosis (membrane retrieval), where the protein cuts off the vesicle from ...

Courtesy of Michael Dustin PASS IT ON: A T cell (blue) interacts with a dendritic cell (yellow) through a molecular pattern described as an immunological synapse (red = adhesion, green = foreign ...

Fruit flies are excellent research models, in part because it is so easy and inexpensive to raise them, and also because they are so well characterized. The DNA of these insects is estimated to be ...

Scientists at HHMI's Janelia Research Campus have discovered a new kind of synapse in the tiny hairs on the surface of neurons. The commonly overlooked protrusions called primary cilia contain special ...