Potassium channels are responsible for the selective permeation of K⁺ ions across cell membranes. K⁺ ions permeate in single file through the selectivity filter, a narrow pore lined by backbone ...

They found that for the mutants displaying calcium blocking, one or two calcium ions are located at the bottom of the selectivity filter. They also discovered that magnesium (Mg 2+) and strontium (Sr ...

The latest Perspectives in General Physiology series examines the ion selectivity of cation-selective channels and transporters. The series appears in the May 2011 issue of the Journal of General ...

This is a preview. Log in through your library . Abstract Since the availability of the first crystal structure of a bacterial Na⁺ channel in 2011, understanding selectivity across this family of ...