Eastern Equine Encephalitis virus (EEEV), an alphavirus, can cause central nervous system infections that can lead to severe encephalitis with a mortality rate of over 30%. A recent study analyzed ...
Many inhibitory receptors that regulate immune cell function recognize a limited number of specific ligands. However, a subgroup of so-called inhibitory pattern recognition receptors (iPRRs) can bind ...
Plants rely on a multilayered immune system in which cell-surface and intracellular receptors detect conserved microbial patterns and rapidly evolving virulence proteins known as effectors. Central to ...
Plants are continuously evolving new immune receptors to ever-changing pathogens. Researchers at the RIKEN Center for Sustainable Resource Science (CSRS) have traced the origin and evolutionary ...
The molecular recognition of ions in aqueous solution has been a major area of chemical research for decades. Nature’s own molecular recognition apparatus largely relies on proteins, but the ...
The opioid-modulating peptides NPFF and RFRP-3 selectively activate NPFFR1 and NPFFR2 through a message–address binding mechanism, where conserved motifs at the peptides’ C-termini engage the ...
Before invaders can be stopped, they must first be detected, and this is accomplished by pattern recognition receptors located on the surface of plant cells. The ability of these receptors to detect ...
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