Explore NMDA receptor modulation and its critical role in neuronal development and cognitive functions like learning and memory.

Receptors are specialised membrane‐bound proteins that play a fundamental role in translating extracellular signals into precise intracellular responses. Integral to cellular communication, these ...

Ecopipam is a first-in-class investigational small-molecule therapy that selectively blocks dopamine-1 (D1) receptors. It is not an antipsychotic. This mechanism differs from currently approved ...

A recent study shows that combining magnetic brain scans with computer models can safely measure how dementia medications affect living human brains. This approach could replace invasive tests and ...

During the double-blind withdrawal period, 41.9% of ecopipam-treated patients relapsed compared with 68.1% of placebo-treated patients. Topline data were announced from a phase 3 trial evaluating ...

Please provide your email address to receive an email when new articles are posted on . The addition of leukotriene receptor antagonists to antihistamines improved urticaria symptoms. The combination ...

BERLIN — Lusvertikimab, a first-in-class interleukin 7 (IL-7) receptor antagonist, demonstrated clinical and endoscopic efficacy in patients with moderate to severe ulcerative colitis (UC) in the ...

Vimgreen Pharmaceuticals, a leading innovator in adenosine signaling modulation, today announced the approval of its Investigational New Drug (IND) application for VG081821 in non‑alcoholic ...

Phase I results demonstrate favorable safety, sustained target engagement, and early signs of anti-tumor activityReinforce EP4 receptor antagonism as a validated, high-value strategy to overcome ...

Opioid antagonists are medications people can take to treat opioid use disorder. They help by reducing withdrawal symptoms, addressing cravings, and managing overdoses. Doctors prescribe opioid ...

The sweet-taste receptor might be the first stop in a metabolic surveillance system for sugar. The receptor is also expressed in certain intestinal cells, where it may facilitate glucose absorption ...