The stereospecific conversion of alkanols plays a pivotal role in synthetic chemistry and drug discovery. Among the substantial advances, the Mitsunobu reaction has long stood out as a powerful ...

Chemists from the National University of Singapore (NUS) have developed a straightforward method to convert common chemicals like carboxylic acids, alcohols, and alkanes directly into valuable alkenes ...

Sequential decarboxylation lets chemists attach electron-rich groups to carbon-carbon double bonds ...

Reactions that completely break carbon-carbon double bonds have particular transformative power in synthesis. Ozonolysis, which splits one alkene into two carbonyl compounds using trioxygen, is widely ...

A team at UNC-Chapel Hill has developed a new process for synthesizing amides in a 100% atom-economical, sustainable fashion using Earth-abundant, environmentally friendly cobalt. UNC-Chapel Hill ...