Following the publication of AlphaFold2 and RoseTTAFold in 2021, the field of protein structure prediction has moved quickly to incorporate these advances into protein engineering. The applications of ...

Enzymes are regarded as the key to sustainable chemistry. Despite major advances in protein design, creating artificial ...

The AI-based program AlphaFold predicts a protein's 3D structure with remarkable accuracy. However, it tends to reduce heterogeneous structures to a single dominant conformation, or shape, and ...

Deep learning methods have been used to augment existing energy-based physical models in 'do novo' or from-scratch computational protein design, resulting in a 10-fold increase in success rates ...

Machine learning-based tools have revolutionized how scientists study protein structure. Here, Nature Chemical Biology speaks to Cecilia Clementi, Bruno Correia and Peilong Lu about progress in ...

BOT or NOT? This special series explores the evolving relationship between humans and machines, examining the ways that robots, artificial intelligence and automation are impacting our work and lives.

AI2 Incubator’s Jenny Cronin (left), interviews David Baker, director of the University of Washington’s Institute for Protein Design. (GeekWire Photo / Charlotte Schubert) The Institute for Protein ...

An international research team led by a Korean scientist has succeeded in designing large-scale protein structures that ...

Biophysicists have elucidated why unexpected structures can sometimes arise during protein design. Artificially designed proteins are usually based on building blocks that obey strict rules of ...

Many of the food industry’s most persistent problems exist not in the realm of business and economics – scaling, costs of materials and the like – but in nature itself. Crops, which the food industry ...