"Humanity is greatly diminished whenever the unborn, or the undocumented, the unemployed, the unhealthy are excluded," Cardinal Blase Cupich said.

Pope Leo, a native of Chicago's south side and a long-time fan of his beloved but beleaguered White Sox, sent a video message on Saturday to a sellout crowd attending Catholic Mass in his honor at their hometown ballpark.

In his first words directed specifically to Americans, Pope Leo XIV told young people on Saturday how to find hope and meaning in their lives through God and in service to others.