Mitochondrial uncoupling refers to processes that dissipate the proton motive force across the inner mitochondrial membrane without ATP synthesis, thereby converting energy into heat and altering ...

Anxiety disorders affect millions of people worldwide, with about 14% experiencing an anxiety disorder in any given year. These conditions are often disabling, and current treatments don’t work well ...

A study led by EPFL shows that Urolithin A, a natural compound, can abolish high anxiety in rats by repairing mitochondrial function in their brain cells, specifically in the nucleus accumbens. The ...

The evidence is amassing that alterations in brain energy metabolism are the first cause of all psychiatric disorders, from anxiety to schizophrenia, autism to Alzheimer’s disease. The metabolic ...

Researchers have developed experimental drugs that encourage the mitochondria in our cells to work a little harder and burn more calories. The findings could open the door to new treatments for ...

Mitochondrial uncoupling proteins (UCPs) comprise a family of inner membrane carriers that dissipate the protonmotive force generated by the electron transport chain, diverting protons from ATP ...

Researchers have developed experimental compounds that make cells burn more calories by subtly tweaking how mitochondria produce energy. Older versions of these chemicals were once used for weight ...