Figure 1. A schematic representation of a lipid nanoparticle encapsulating mRNA. As this new form of biotechnology makes a leap of progress, so too do the analytical approaches supporting its ...

Liquid chromatography - mass spectrometry (LC-MS) combines two approaches to separate and identify molecules or compounds present in a sample. High performance liquid chromatography (HPLC) separates ...

How is LC-MS performed? The sample first undergoes ionization before entering the mass spectrometer. Commonly used ionization methods are electrospray ionization and atmospheric pressure chemical ...

LC-MS/MS has been increasingly adopted by clinical laboratories due to the potential it has for increased sensitivity and specificity over more commonly used analytical techniques. However, ...

This is the final article in this series discussing HPLC oligonucleotide separations. This article will discuss LC/MS analysis of failure sequences, phosphorothioate modified siRNAs, CpG methylated ...

Liquid Chromatography-Mass Spectrometry (LC-MS) combines liquid chromatography (LC) with mass spectrometry (MS) to separate, identify, and quantify compounds. It is a powerful analytical technique ...

New users of the LC/MS laboratory and Sample Preparation Lab are required to engage in hands-on orientation to facility operations (e.g., laboratory access, scheduling, general use of equipment, ...

Learn all the essential theory of liquid chromatography and LC-MS along with hands-on practicals in the laboratory. This course has been approved by the Royal Society of Chemistry for purposes of ...

The Agilent 6475 triple quadrupole LC/MS is the latest evolution of the reliable LC/MS/MS workhorse customers trust the most. This sensitive, robust, and versatile triple quadrupole mass spectrometer ...