Scientists at Feinberg are reshaping scientific understanding of the cell's tiniest components—structures once thought to be ...

Gap junctions are specialised intercellular channels that facilitate direct communication between adjacent cells by allowing the regulated exchange of ions, second messengers and small metabolites.

Now, MIT engineers have found that this "intercellular" fluid plays a major role in how tissues respond when squeezed, pressed, or physically deformed. Their findings could help scientists understand ...

Intercellular forces generate distinct patterns of extrusion: high compressive forces (top panel) drive apoptotic cell extrusion toward the upper side, while lower compressive forces (bottom panel) ...

TNBCs rely on fatty acid oxidization (FAO) to fuel tumor growth by breaking down surrounding adipose tissue through lipolysis. Gap junctions, particularly involving GJB3 and connexin 31 (Cx31), ...

Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated. This is ...