Researchers identify the hippocampus and microglia as the "tipping point" that determines if chronic pain leads to depression ...

Scientists have uncovered a brain mechanism that may explain why chronic pain leads to depression in some people but not ...

Changes to one's hippocampus, the brain's memory centre, in response to prolonged pain could be an important factor for why ...

The complexity of the human brain is unparalleled. Fortunately, thanks to constant progress in neuroscience over the past decades, we have started to make some sense of the human brain. For instance, ...

Early in the pain process, newly generated neurons in the dentate gyrus showed increased activity – suggesting the brain initially mounts a protective response to persistent pain. Over time, however, ...

A staggering 280 million people suffer with depression worldwide, reports the World Health Organization, and many experience debilitating symptoms that are not effectively treated by currently ...

Scientists have uncovered a brain mechanism that may explain why chronic pain leads to depression in some people but not others, according to research published in Science. The findings challenge the ...