HBsAg decline at week 24 and baseline HBsAg levels are better predictors of functional cure than novel virologic markers, while on-treatment HBV RNA and HBeAg levels and dynamic changes are the most ...

Please provide your email address to receive an email when new articles are posted on . The cumulative probability of functional cure was 14.53% at a mean age of 25.75 years. The annual cure rate was ...

Hepatitis B virus (HBV) infection is a major risk factor for cirrhosis and liver cancer, and its treatment continues to be difficult. We previously demonstrated that a dopamine analog inhibited the ...

Natural History of Chronic Hepatitis B Based on REVEAL-HBV Study Findings As previously mentioned, the natural history of chronic hepatitis B has been classified into three phases: immune tolerance, ...

Seven patients with cHBV remain off all treatment and continue to maintain low levels of HBV DNA and HBsAg for at least one and half years post- AB-729 treatment AB-161 provides robust anti-HBV ...

The combination of age and baseline hepatitis B s-antigen (HBsAg) level can help predict hepatitis B virus (HBV) relapse in patients who achieve hepatitis B e-antigen (HBeAg) loss or seroconversion ...

Chronic hepatitis B virus (HBV) is the most common cause of liver disease throughout the world. [1] More than 300 million persons are currently estimated to be infected with HBV worldwide. The highest ...

PASADENA, Calif.--(BUSINESS WIRE)-- Arrowhead Pharmaceuticals Inc. (NASDAQ: ARWR) today announced Phase 2 clinical data on a double combination of JNJ-3989 (formerly ARO-HBV) and a nucleos(t)ide ...

F. Hoffmann-La Roche Ltd. has discovered benzothiazolyl bicyclo [1.1.1]pentane derivatives acting as hepatitis B virus (HBV) HBeAg and HBsAg secretion inhibitors, reported to be useful for the ...

Hepatitis B virus e antigen positive (HBeAg+) subjects dosed with once-daily 300mg ALG-000184 + entecavir for up to 48 weeks demonstrated: SOUTH SAN FRANCISCO, Calif., Nov. 10, 2023 (GLOBE NEWSWIRE) - ...