Breast cancers at all stages are defined by the structure of their genomes, researchers find. Targeting these processes early is likely to offer unexpected therapeutic avenues. Breast cancers can be ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how ...

“We’ve long known that mutations drive cancer,” said Dr. Martin Rivas, a cancer researcher at Sylvester Comprehensive Cancer Center. “But this work shows that architecture—the way DNA folds—can be ...

Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the host's cellular machinery to make new copies of themselves. Herpes simplex ...

Life begins with a quiet but precise choreography inside the nucleus. For decades, scientists believed that a newly ...

CHICAGO --- In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed ...

The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

For decades, scientists believed a fertilized egg’s DNA began as a shapeless mass, only organizing itself once the embryo switched on its genes. But new research reveals that the genome is already ...

The origin of eukaryotes -- Genome size and organismal complexity -- The human genome -- Why population size matters -- Three keys to chromosomal integrity -- The nucleotide composition landscape -- ...