Scientists have often thought of cells as small, bustling cities with parts that resemble factories, power grids and shipping ...

When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways ...

Our cells' membranes have many functions. They not only provide mechanical protection but also precisely control which ...

Hello, I'm Scat.Last time, we thought about the state and quality of cells, starting from the question of what a "good cell" ...

An autoinhibitory domain in the C-terminal tail of the TMEM63B, a mechanosensitive lipid scramblase, helps maintain its ...

Cholesterol is one of the most famous molecules in medicine, blamed for heart attacks and clogged arteries, yet it is also an ...

David Baker’s research team at the Institute for Protein Design has unveiled a new technique for sequestering membrane proteins (Science 2026, DOI: 10.1126/science.adr3817). Proteins bound in cell ...

In the pre-synapse, vesicle fusion is a crucial process for neurotransmitter release in the nervous system. Under physiological conditions, synaptotagmin-1 (Syt1) locks synaptic vesicles in a priming ...