One of the most effective and widely used chemotherapy drugs in the world is also one of the most feared for a side effect ...

Researchers develop a 3D cell culture system to test how inhibiting fibroblast activities can help treat lung cancer. To simulate the tumor microenvironment and mimic real tissues, the team ...

Fibroblasts build and maintain the extracellular matrix, or physical scaffolding for cells, in the connective tissues within the body. It is believed that cancerous tumors can recruit nearby ...

Playing a role in a variety of biological processes, including the promotion of neuronal plasticity, embryonic development, epithelial cell migration, and tumor growth and invasion, basic fibroblast ...

This article is based on a poster originally authored by Fiona Leslie, Chloe Whiting, and Megan Webster. TGF-β1-mediated activation of fibroblasts, their transition to α-SMA-expressing myofibroblasts, ...