DNA double-strand breaks (DSBs) represent one of the most deleterious forms of genomic insult, challenging the cell’s capacity to maintain integrity and prevent oncogenic rearrangements. Repair of ...
Nonhomologous end joining (NHEJ) is the principal pathway for repairing DNA double-strand breaks (DSBs) throughout the cell cycle, acting rapidly to preserve genomic integrity when a sister chromatid ...
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