Monkey experiments hint at a "motivation brake" pathway between two brain regions. Manipulating it may lead to new treatments ...

Researchers suggest that, from a clinical perspective, the findings provide mechanistic insight into motivational deficits central to psychiatric disorders.

Researchers have discovered a break that could help ease a common symptom of depression. Discover more about it.

Ever wonder why starting feels harder than finishing? Brain research shows stress can quietly block motivation before action ...

Most of us know the feeling: maybe it is making a difficult phone call, starting a report you fear will be criticized, or ...

Exercise’s positive effect on depression is well-known, but not how it produces its anti-depressant effects. After reviewing a broad range of studies into how depression and physical activity affect ...

Depression still remains a taboo as well as a misunderstood topic despite much growing awareness. One of the most common and ...

Philadelphia, May 1, 2025 – New research shows that individuals who have recovered from depression are generally less willing to exert effort to pursue potential rewards compared to those who have ...

A recent research review shows that exercise may be nearly as effective as therapy in managing depression. However, experts ...

One of the key features of depression is the lack of motivation to do things that you know you should really do. For example, you may think that you don't have the motivation to exercise, or spend ...

If you struggle with depression, you probably know how heavy it can feel, as if an invisible weight is pulling you down. One of the most painful ironies of depression is that it often drains people of ...