The cerebral cortex, the brain's outermost region responsible for higher cognitive functions, depends on a highly ordered, layered structure. Its proper development requires newly generated neurons to ...

Researchers found that nonsense-mediated mRNA decay, via the UPF2 protein, is crucial for neuronal migration and cortical ...

In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA. They found that the defect is highly sensitive to an ...

SEATTLE, WASH. — October 9, 2025 — In an exciting scientific first, researchers at the Allen Institute successfully designed a new gene therapy that reversed symptoms related to SYNGAP1-related ...

CHAPEL HILL – For decades, scientists have thought the faulty neural wiring that predisposes individuals to behavioral disorders like autism and psychiatric diseases like schizophrenia must occur ...

A research team led by scientists at Queen Mary University of London and University College London (UCL) has found new clues about how the brains of people with Down syndrome develop differently from ...

In an era intent on unraveling the mysteries of the brain, we are apt to view problems ranging from depression to hyperactivity as signs of defective brain chemistry. However, over-focusing on the ...

An international research team led by the Leibniz Institute on Aging – Fritz Lipmann Institute (FLI) in Jena, Germany, and the University of Tennessee Health Science Center, Memphis, USA, has ...

These are a class of brain disorders that can lead to severe and debilitating symptoms including intellectual disability, epilepsy, motor problems, and risk-taking behaviors in humans. In most cases, ...