Nature

Multifaceted roles of MHC class I and MHC class I–like molecules in T cell activation

In addition to the TCR and classical MHC class I, MHC class 1–like molecules can interact with a variety of receptors that play a role in T cell activation. Engagement of NKG2D on CMV-specific αβ CD8 ...
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A missing link in the MHC class divergence puzzle: Class II came first

Which came first, MHC class I or MHC class II? For decades, it has been debated which of these two similar classes came first in evolution. Now, Keiichiro Hashimoto and his group at Fujita Health ...
Nature

MHC class I typing in a songbird with numerous loci and high polymorphism using motif-specific PCR and DGGE

The major histocompatibility complex (MHC) has a central role in the specific immune defence of vertebrates. Exon 3 of MHC class I genes encodes the domain that binds and presents peptides from ...
ascopubs.org

Major histocompatibility complex class I (MHC 1) expression in clear cell renal cell carcinoma: Correlation with clinical outcome.

Assessment of time from cytoreductive nephrectomy (CN) to initiation of targeted therapy (TT) in patients with metastatic renal cell carcinoma (mRCC). This is an ASCO Meeting Abstract from the 2014 ...