CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by modulating enhancer-promoter (EP) interactions. However, acute depletion of ...

Biology is never as straightforward as we learned in high school. Take sex-linked chromosomes as an example: we’re taught that biological males get XY chromosomes while biological females get two ...

A new study on dogs found that chromatin's spatial structure has a significant role in the evolution of social behavior. Chromatin, the compact form of DNA, not only packages genetic material but also ...