Chemotherapy-induced peripheral neuropathy (CIPN) is a common and potentially dose-limiting adverse effect of platinum-based chemotherapies that features pain and sensory deficits in the periphery.

From 'Killing Cancer with Poison' to Molecular Targeted, Immunotherapy, and Personalized MedicineThe history of anticancer ...

Preclinical findings suggest that psilocybin may protect sensory nerves from chemotherapy toxicity, but clinical trials are ...

One of the most effective and widely used chemotherapy drugs in the world is also one of the most feared for a side effect ...

Many cancer treatments work by exploiting weaknesses in tumor cells, overwhelming their ability to survive, repair damage or ...

Using tiny particles shaped like bottlebrushes, MIT chemists have found a way to deliver a large range of chemotherapy drugs directly to tumor cells. To guide them to the right location, each particle ...

Scientists have devised a blueprint for boosting anti-cancer drugs’ effectiveness and lowering their toxicity by attaching the equivalent of a lead sinker onto the drugs. This extra weight makes the ...

For patients with resectable esophageal adenocarcinoma, perioperative chemotherapy with fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) leads to improved survival compared with ...

Patients on an experimental drug called gotistobart lived a median of 18.5 months after starting treatment for advanced squamous non-small cell lung cancer, compared with 10.0 months for patients ...

CLEVELAND, Ohio — When we hear that a friend has breast cancer, we know they’re in for a rough patch but will probably be fine in the end. The reaction is very different if the diagnosis is aggressive ...

Most people who undergo chemotherapy do not develop heart failure. However, specific chemotherapy drugs may significantly increase your risk of heart failure and other cardiac problems. Chemotherapy ...