Bacteria coordinate DNA replication, cell growth and morphological changes via a tightly regulated cell cycle. Central to this process is a network of signalling pathways, transcription factors and ...
The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...
The progression of the cell cycle is not solely driven by canonical regulators such as cyclins and cyclin-dependent kinases (CDKs); it is intimately coupled to cellular metabolism. Cells must ...