Opus Genetics (IRD) rated Hold: valuation hinges on AAV gene therapy success. Track LCA5 Phase 3, 2026 data catalysts & ...

A new study shows that subretinal adeno-associated virus 8 (AAV8) injections cause proinflammatory T-cell immune response against the transgene product. According to the study, published in the ...

A research team at the University of Osaka has unveiled the molecular mechanism behind genome ejection from adeno-associated virus (AAV) vectors, a crucial delivery vehicle in gene therapy. The study, ...

Adeno-associated viruses (AAV) have emerged as pivotal delivery vehicles for gene therapy due to their overall safety (less immunogenic), efficiency (broad tropism), and long-term gene expression.

(A) Generation of the novel AAVT42 vector by directed evolution and in vivo screening. The cap genes of AAV1, AAV2, AAV3B, AAV4, and AAV6-9 were mixed, after digestion, denaturation, and reannealing, ...

While there is no cure for ANCA-associated vasculitis (AAV), treatment is usually very effective at bringing it under control and preventing life-threatening complications. This group of rare ...

Age-related macular degeneration (AMD) is the leading cause of blindness among older adults. The exudative or ‘wet’ form of the disease is characterized by the growth of abnormal blood vessels from ...