The San Francisco 49ers will hold their lone full practice of a shortened week on Tuesday evening as they prepare for Thursday night's pivotal NFC West clash against the Los Angeles Rams.

The Philadelphia Eagles’ defensive performance in Super Bowl LIX shows what the San Francisco 49ers need to address during the 2025 NFL offseason.

If the 49ers dethrone the Eagles next season, that will could yield a historic win in Super Bowl LX at Levi’s Stadium.

The 49ers entered the game battered with injuries, as they have been all season, but with the security that they have only been swept by the Rams for a full season once in the Sean McVay era.

Los Angeles Rams defensive ... collecting a sack on 49ers quarterback Brock Purdy to end their Week 15 Thursday night matchup. Watch highlights from the AFC Championship Game between the Buffalo ...

Week 15 has arrived, and the San Francisco 49ers will host the Los Angeles Rams on Thursday Night Football. There are countless ways to bet this game across the best PA sportsbooks, but today we ...