The Tennessee Titans had no answer for Brock Purdy and the San Francisco offense in a Week 15, 37-24, loss to the 49ers .

It's clear the 49ers are relying on Pearsall to become Aiyuk's successor in the receiving corps — this season and in the future.

The Tennessee Titans and San Francisco 49ers have officially announced their inactives ahead of a Week 15 game.

Preview the San Francisco 49ers' NFL week 15 matchup with the Titans, including betting odds, tips, trends, and game information.

Here's a look at the studs and duds (and those in between) from the Tennessee Titans' 37-24 loss to the San Francisco 49ers in Week 15.

Need to know. Brock off a bye. 49ers quarterback Brock Purdy has played two games off a bye in his career, and he has been nearly perfect in both. In those two g

San Francisco 49ers QB Brock Purdy's quick throw to TE George Kittle resulted in a 24-yard gain in the team's Week 15 matchup.

The San Francisco 49ers completed their cruise through the soft underbelly of their schedule Sunday with a 37-24 victory against the Tennessee Titans. In a stretch against the Arizona Cardinals, Carolina Panthers,