Israel and Iran exchange missile attacks for a third day; nuclear sites hit, death tolls rise, airspace shut, U.S. warns Tehran against retaliation.

Most of those confirmed dead were women and children, according to the authorities, although they have yet to publicly name the victims.

Missiles and projectiles were seen in the skies over Jerusalem and Tel Aviv early on Sunday as Tehran unleashed a fresh attack on Israel which in turn launched an expanded assault on Iran.

Israeli Iron Dome air defense system fire to intercept missiles over Tel Aviv as others explode and traces fly over Jerusalem during a missile attack by Iran in retaliation for deadly Israeli attacks on nuclear sites and military leaders.

Israel and Iran continue to exchange airstrikes strikes into the weekend, leaving multiple people dead outside Tel Aviv. NBC News' Matt Bradley reports from Bat Yam, a suburb of Tel Aviv, where a residential building was hit by a missile.

DUBAI — Israel unleashed airstrikes across Iran for a third day Sunday and threatened even greater force as some Iranian missiles evaded Israeli air defenses to strike buildings in the heart of the country. Planned talks on Iran’s nuclear program, which could provide an offramp, were canceled.

Onlookers gathered on Saturday at a central Tel Aviv residential building next door to Israel’s defense headquarters that was damaged after it took a hit from what appeared to be shrapnel from an overnight missile barrage from Iran.

Air raid sirens and booms rang out in Jerusalem and Tel Aviv early Sunday, AFP journalists said, as Israel and Iran exchanged fire for a third day. Israel’s military wrote in a post on X that millions of Israelis were “running for shelter as sirens sound” in dozens of cities and communities around the country.