000671 - DBA2 Strain Details - The Jackson Laboratory
WEB000671 DBA/2J DBA/2J is a widely used inbred strain. Some characteristics include low susceptibility to developing atherosclerotic aortic lesions, high-frequency hearing loss, susceptibility to audiogenic seizures, development of progressive eye abnormalities that closely mimic human hereditary glaucoma, affinity for methamphetamine, and ...
DBA/2J Mouse Strain Characteristics - Maze Engineers
WEBDec 4, 2018 · The DBA/2J mouse strain is a very commonly used inbred strain. It often serves in experimental studies as a contrast to the most popular C57BL/6J strain, as their genotypes and phenotypes are opposed in a number of respects.
013141 - Strain Details - The Jackson Laboratory
WEB013141 D2.B10- Dmd mdx /J The D2.B10 (DBA/2-congenic) Dmd mdx mouse (also referred to as DBA/2J-mdx or D2-mdx mice) may be a superior Duchenne muscular dystrophy model as it better recapitulates several of the human characteristics of DMD myopathology (lower hind limb muscle weight, fewer myofibers, …
Body Weight Info - Strain 000671 DBA2 - The Jackson Laboratory
WEBBody Weight Information for JAX® Mice Strain DBA/2J - Stock Number 000671. Groups of 30 females and 30 males were weighed weekly. Mice were fed a diet containing 6% fat (LabDiet® 5K52 formulation).
Age-related Changes in Eye, Brain and Visuomotor Behavior in the DBA/2J …
WEBMar 15, 2018 · Specifically, DBA/2J (D2) mice represent late onset, chronic pigmentary glaucoma due to elevations in IOP that result from melanosomal protein mutations.
DBA 2 Mouse - an overview | ScienceDirect Topics
WEBThe DBA/2 lineage of mice, including DBA/2J (74–77), DBA/2NNia (78–80), and AKXD-28/TyJ (81) all develop age-related forms of glaucoma that include iris disease, increased IOP, and retinal ganglion cell loss. The disease-causing mutations have been identified in DBA/2J (74,75).
DBA/2J Strain Detail MGI Mouse MGI:2684695 - The Jackson …
WEBSep 3, 2024 · View mouse strain DBA/2J : mutations, QTL, phenotypes, diseases, and references.
MPD: Mouse strain: DBA/2J - The Jackson Laboratory
WEBThe file contains all strain survey measured phenotypes where DBA/2J was tested, along with measured means and summary statistics. Field names are given in the first row. The file includes some measurement metadata fields as …
BCLXL gene therapy moderates neuropathology in the DBA/2J …
WEBAug 10, 2021 · In the DBA/2J mouse model of glaucoma, mCherry-BCLX L conferred extended protection to the retina and the ON that exceeded the reported protective effect of genetic deletion of Bax.
High-throughput sequencing of the DBA/2J mouse genome
WEBJul 23, 2010 · The DBA/2J mouse is not only the oldest inbred strain, but also one of the most widely used strains. DBA/2J exhibits many unique anatomical, physiological, and behavior traits. In addition, DBA/2J is one parent of the large BXD family of recombinant inbred strains [1].
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