BALB/c - Wikipedia
WEBBALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation. [1]
000651 - BALBc Strain Details - The Jackson Laboratory
WEBKey traits include a susceptibility to developing the demyelinating disease upon infection with Theiler's murine encephalomyelitis virus. The BALB/cJ substrain is susceptible to <i>Listeria</i>, all species of <i>Leishmania</i>, and several species of <i>Trypanosoma</i>, but is resistant to experimental allergic orchitis (EAO).
BALB/c Mice | Charles River
WEBThe BALB/c mouse is among the most widely used inbred models used in biomedical research, and is particularly utilized in immunology and infectious disease research. Their ability to produce plasma cell tumors within soft tissue is important in the production of monoclonal antibodies (mAbs).
BALB/c - an overview | ScienceDirect Topics
WEBBALB/c mice are inbred strain and now over 230 generations from their origin in New York in 1920. BALB/c mice are distributed globally and among the five most widely used inbred strains in biomedical research, particularly in immunology and infectious disease research.
C57BL/6 and BALB/c Mouse Models | Cyagen
WEBMar 30, 2020 · In C57BL/6 mice, Th1 immune response and IFNγ production play the key role. Alternately, it is easier to induce Th2 immune response in BALB/c mice, which is very common in infectious diseases and allergic reactions. BALB/c mice tend to produce a stronger humoral response than C57BL/6 mice.
The BALB/c Mouse: Genetics and Immunology | SpringerLink
WEBToday the BALB/c mouse is among the five most widely used inbred strains in biomedical research and a particular favorite in immunology and infectious disease research.
The BALB/c Mouse Model for the Evaluation of Therapies to Treat ...
WEBMar 3, 2023 · With respect to therapeutic evaluation, the BALB/c mouse model is a robust model of infection, typically using females 6–8 weeks old (Table 1). A target dose of approximately 20–50 LD 50 equivalents achieves an acute, lethal infection.
Elucidating different pattern of immunoregulation in BALB/c
WEBJan 15, 2021 · Our data indicate that Treg dominate the regulation of immune responses in BALB/c and F1 mice, while multiple regulatory layers exist in C57BL/6 mice that may compensate for the absence of Treg.
Clinical hematological and biochemical parameters in Swiss, BALB/c ...
WEBDec 18, 2020 · The determination of values for hematological and biochemical parameters in Swiss, BALB/c, C57BL/6 and B6D2F1 mice is important in the choice of experimental model and study design because of the significant differences in these parameters between lineages, genders and routes of blood collection.
BALB/cJ and BALB/cByJ: How can I choose? I’m so confused!
WEBLearn how the original BALB/c strain separated into two major substrains (BALB/cJ and BALB/cByJ) and how to decide which one to use for your research.